Research Studies Currently Recruiting
Click on the study name below for more information including study description, recruitment details and compensation.
Eligibility: Participants are eligible for this study if they are 45 years of age or older, have suffered previous bleeding in the head (within or around the brain) called intracranial hemorrhage, and have an abnormal heart rhythm called atrial fibrillation.
About the study: The main purpose of this study is to find out if the use of edoxaban, an anticoagulant or drug that slows blood clotting and has a similar safety profile as aspirin, is better at reducing the risk of stroke compared to other treatments that avoid using drugs that slow blood clotting in participants that have had previous bleeding in the head and have atrial fibrillation. Participants will be randomly assigned (50/50 chance) to receive either edoxaban or non-anticoagulant medical therapy (no specific therapy for the prevention of blood clots or therapy with aspirin or another antiplatelet drug). Both the participant and doctor will know which group the participant is assigned to. After the first visit, participants will be seen every 6 months for follow up. Tasks that will be completed at study visits include a questionnaire, possible blood draws (if not completed clinically), vital signs (ie blood pressure and heart rate), review of medical history and current medications, and dispensing study medication (if applicable). Participants will also be sent home with a blood pressure machine to record their blood pressures 2-3 times per week between study visits. The average length of being in the study is 2 years, but can range between 1 and 3 years.Using blood thinners in persons with a common abnormal heart rhythm called atrial fibrillation is very effective at preventing stroke from blood clots. However, using these medications in patients with atrial fibrillation who have had previous bleeding in the head is of major uncertainty and concern. It requires balancing the benefit of preventing stroke against the higher chance of another bleed. As these drugs have never been tested properly in patients with previous bleeding in the head, there currently exist a lot of different practices depending on the doctor. These different practices without proper evidence put patients at risk for harm.
If you are interested in this study please email Cathy Moreau – firstname.lastname@example.org
Researchers: Dr. Shoamanesh, Dr. Catanese, Dr. Ng
Exploring the Relation between Fitness and Executive Functioning in Young Adults with ADHD
Researchers are now recruiting young adults between 17-30 years of age who have been clinically diagnosed with ADHD.
The Department of Kinesiology is now recruiting young adults between 17-30 years of age who have been clinically diagnosed with ADHD to take part in an exercise psychology study. The experimental sessions will be conducted at the NeuroFit Lab and will take 2 hours to complete across 2 visits. There will be an additional third visit (15-20 minutes) where you will complete body composition scan. The first visit will involve the completion of a maximal exercise test which includes breathing into a mouth piece and biking on a cycle ergometer. The second visit will occur approximately 48 hours later, where you will complete a series of questionnaires and three cognitive tasks of executive function. During the cognitive tasks Functional Near Infrared Spectroscopy (fNIRS) neuroimaging will be used to measure your brain activation. FNIRS is a non-invasive neuroimaging technique that uses a cap with optodes to emit light and detectors to calculate changes in blood flow, in order to measure brain activity within the prefrontal cortex. Body composition will be assessed using a BodPod body scan, which is a painless, non-invasive procedure. You will be required to sit in a small comfortable chamber for about 5 minutes while body composition is assessed. This visit can be scheduled anytime within a week of the experimental sessions.
Compensation – $40 and full results of a body composition analysis (typically $50-80 to complete otherwise)
Researchers – Michelle Ogrodnik and Dr. Jennifer Heisz (PI)
Email – email@example.com
Thank you for your recent interest regarding participation in a Department of
Kinesiology research study. This study will take approximately 2 hours to complete across 2 visits. You will earn $20 or 2 SONA credits for your participation in this study ($10 or 1 SONA credit for each study session attended. In part, the first visit of this study involves completing a set of questionnaires and six different exercise and non-exercise tasks. The second visit involves a non-exercise task followed by a computer game to earn time spent engaging in different tasks.Throughout the study, you will be asked to provide ratings of fatigue, boredom, and mood. There are potential risks and discomforts associated with the exercise testing procedures which are similar to those associated with any form of strenuous physical activity.
To be eligible for participation in this study you must:
– Be 17-30 years of age
– Be in good health
– Have the intention of being physically active over the next three months
– Speak English as your first language
$20 or 2 SONA Credits
Sheereen Harris, Dusan Kovacevic, & Steven Bray (PI)
Sheereen Harris: firstname.lastname@example.org
This research study has been approved by the McMaster Research Ethics Board.